{"id":35,"date":"2022-06-24T21:13:54","date_gmt":"2022-06-24T12:13:54","guid":{"rendered":"https:\/\/mcm-www.jwu.ac.jp\/~Nakajima\/blog\/?page_id=35"},"modified":"2026-03-03T16:01:25","modified_gmt":"2026-03-03T07:01:25","slug":"%e7%a0%94%e7%a9%b6%e6%a5%ad%e7%b8%be","status":"publish","type":"page","link":"https:\/\/mcm-www.jwu.ac.jp\/~Nakajima\/blog\/?page_id=35","title":{"rendered":"\u7814\u7a76\u696d\u7e3e"},"content":{"rendered":"\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill\"><a class=\"wp-block-button__link has-vivid-green-cyan-background-color has-background wp-element-button\" href=\"#paper\">\u5b66\u8853\u8ad6\u6587<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-vivid-green-cyan-background-color has-background wp-element-button\" href=\"#presentation\">\u5b66\u4f1a\u767a\u8868<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:37px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-left has-light-green-cyan-background-color has-background\" id=\"paper\" style=\"font-size:20px;line-height:0\">\u5b66\u8853\u8ad6\u6587<\/p>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-6a410fe4f914036069bf7ec948795504\">2026<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.3390\/epidemiologia7020034\">Comorbidities and Concomitant Medications in Middle-Aged Japanese People According to the Charlson Comorbidity Index and Age: Results of the NDB-K7Ps-Study-3.<\/a>\u00a0Sekine, A.; Nakajima, K.\u00a0<em>Epidemiologia<\/em>\u00a0<strong>2026<\/strong>,\u00a0<em>7<\/em>, 34. <a href=\"https:\/\/doi.org\/10.3390\/epidemiologia7020034\">https:\/\/doi.org\/10.3390\/epidemiologia7020034<\/a><\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-b5079ef2b70e7ebc87044e3108f24d50\">2025<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Correlations Between Wald Chi-Squared Values and Standardized Beta-Coefficients in Regression Analysis and Feature Importance Calculated Using Machine Learning.\u00a0Nakajima K, Sekine A.\u00a0<em>AI Clin Med<\/em>. 2025;1:e10. doi:<a href=\"https:\/\/doi.org\/10.14740\/aicm10\">10.14740\/aicm10<\/a><\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-large-font-size\">2024<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.14740\/jocmr6057\">High Blood Glucose After Starch Loading in Young Women With Small Increase in Salivary Amylase: Another Crucial Role of Postprandial Salivary Amylase. <\/a>Sekine A, Nakajima K.\u00a0.\u00a0<em>J Clin Med Res<\/em>. 2024;16(10):465-471. doi:10.14740\/jocmr6057<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39084944\/\">Possible pitfalls in the prediction of weight gain in middle-aged normal-weight individuals: Results from the NDB-K7Ps-study-2<\/a>. Kei Nakajima,\u00a0Airi Sekine,\u00a0Ryoko Higuchi,\u00a0Mai Enokido,\u00a0Sadako Matsui Obes Res Clin Pract. 2024 Jul-Aug;18(4):255-262. doi: 10.1016\/j.orcp.2024.07.004. Epub 2024 Jul 31.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.cureus.com\/articles\/223391-moderate-to-heavy-alcohol-consumption-may-cause-a-significant-decrease-in-serum-high-density-lipoprotein-cholesterol-in-middle-aged-women-a-cohort-study-of-the-national-database-study-in-the-kanto-7-prefectures-4#!\/\">Moderate-to-Heavy Alcohol Consumption May Cause a Significant Decrease in Serum High-Density Lipoprotein Cholesterol in Middle-Aged Women: A Cohort Study of the National Database Study in the Kanto 7 Prefectures-4.<\/a><strong>\u00a0<\/strong>\u00a0Airi Sekine, Kei Nakajima. Cureus 16(3): e55467. doi:10.7759\/cureus.55467 2024\u5e743\u67084\u65e5<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-large-font-size\">2023<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a data-wplink-edit=\"true\" href=\"https:\/\/www.mdpi.com\/2673-3986\/4\/4\/34\" data-type=\"URL\" data-id=\"https:\/\/www.mdpi.com\/2673-3986\/4\/4\/34\" target=\"_blank\" rel=\"noreferrer noopener\">Agreement in All-in-One Dataset between Diagnosis and Prescribed Medication for Common Cardiometabolic Diseases in the NDB-K7Ps.<\/a>\u00a0Airi Sekine, Kei Nakajima.\u00a0<em>Epidemiologia<\/em>\u00a02023,\u00a0<em>4<\/em>(4), 370-381;\u00a0<a href=\"https:\/\/doi.org\/10.3390\/epidemiologia4040034\">https:\/\/doi.org\/10.3390\/epidemiologia4040034<\/a>\u00a02023\u5e7410\u67082\u65e5<\/li>\n\n\n\n<li><p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37002060\/\" data-type=\"URL\" data-id=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37002060\/\">Relationship between non-restorative sleep and body weight in a general population: Results of NDB-K7Ps-Study-1<\/a>. Kei Nakajima,\u00a0 Airi Sekine. Obesity research &amp; clinical practice\u00a02023\u5e743\u670829\u65e5\u00a0\u00a0<\/p><\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-buttons is-horizontal is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-7e5fce0a wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill\"><a class=\"wp-block-button__link has-vivid-green-cyan-background-color has-background has-small-font-size has-custom-font-size wp-element-button\" href=\"https:\/\/mcm-www.jwu.ac.jp\/~Nakajima\/blog\/wp-content\/uploads\/2023\/06\/HP\u3000ORCP\u65e5\u672c\u8a9e.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">\u65e5\u672c\u8a9e\u8981\u7d04<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-large-font-size\">2022<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36128008\/\" target=\"_blank\" rel=\"noreferrer noopener\">U-Shaped Relationship Between Proteinuria and High-Density Lipoprotein Cholesterol: Results of Cross-Sectional and Six Years Cohort Studies (KITCHEN-10).<\/a> Manami Igata,\u00a0Kei NakajimaJ Clin Med Res.\u00a02022 Aug;14(8):300-308. <\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/37237573\">Elevated All-Cause Mortality among Overweight Older People: AI Predicts a High Normal Weight Is Optimal.<\/a>Kei Nakajima, Mariko YunoGeriatrics (Basel, Switzerland)\u00a07(3)\u00a02022\u5e746\u670816\u65e5\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/36889596\">High Aspartate Aminotransferase\/Alanine Aminotransferase Ratio May Be Associated with All-Cause Mortality in the Elderly: A Retrospective Cohort Study Using Artificial Intelligence and Conventional Analysis.<\/a>Kei Nakajima, Mariko Yuno, Kazumi Tanaka, Teiji NakamuraHealthcare (Basel, Switzerland)\u00a010(4)\u00a02022\u5e744\u67082\u65e5\u00a0\u00a0<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-large-font-size\">2021<\/p>\n\n\n\n<ul id=\"block-e546d339-9be4-4aec-a172-dbdf16952854\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/36157446\">Association of Serum High-Density Lipoprotein Cholesterol with High Blood Pressures at Checkup: Results of Kanagawa Investigation of Total Checkup Data from the National Database-9 (KITCHEN-9).<\/a>Kei Nakajima, Manami Igata, Ryoko Higuchi, Kotone Tanaka, Kaori Mizusawa, Teiji NakamuraJournal of clinical medicine\u00a010(21)\u00a02021\u5e7410\u670830\u65e5\u00a0\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/36157448\">Fasting biochemical hypoglycemia and related-factors in non-diabetic population: Kanagawa Investigation of Total Check-up Data from National Database-8.<\/a>Kotone Tanaka, Ryoko Higuchi, Kaori Mizusawa, Teiji Nakamura, Kei NakajimaWorld journal of diabetes\u00a012(7) 1131-1140\u00a02021\u5e747\u670815\u65e5\u00a0\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/36157447\">Potential Role of Artificial Intelligence for the Previous Study Using Traditional Analysis.<\/a>Kei Nakajima, Manami Igata, Ryoko HiguchiJournal of clinical medicine research\u00a013(7) 409-411\u00a02021\u5e747\u6708\u00a0\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/32629909\">Association between extremely high high-density lipoprotein-cholesterol and hypertensive retinopathy: results of a cross-sectional study from Kanagawa Investigation of Total Checkup Data from the National Database-6 (KITCHEN-6).<\/a>Kei Nakajima, Ryoko Higuchi, Kaori Mizusawa, Teiji NakamuraBMJ open\u00a011(5) e043677\u00a02021\u5e745\u670811\u65e5\u00a0\u00a0<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-large-font-size\">2020<\/p>\n\n\n\n<ul id=\"block-dae329e6-0921-429b-9fff-8ba8468c8caf\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/32629910\">Unexpectedly High Prevalence of Breakfast Skipping in Low Body-Weight Middle-Aged Men: Results of the Kanagawa Investigation of Total Checkup Data from the National Data Base-7 (KITCHEN-7).<\/a>Kei Nakajima, Ryoko Higuchi, Kaori Mizusawa Nutrients\u00a013(1)\u00a02020\u5e7412\u670830\u65e5\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/28427677\">The association of low serum salivary and pancreatic amylases with the increased use of lipids as an energy source in non-obese healthy women<\/a>Kei Nakajima, Ryoko Higuchi, Taizo Iwane, Ayaka IidaBMC Research Notes\u00a013(1)\u00a02020\u5e7412\u6708\u00a0\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/36157449\">Trace Proteinuria and the Incidence of Overt Proteinuria After Five Years: Results of the Kanagawa Investigation of the Total Checkup Data From the National Database-5 (KITCHEN-5).<\/a>Kei Nakajima, Ryoko Higuchi, Kaori Mizusawa. Journal of clinical medicine research\u00a012(9) 618-623\u00a02020\u5e749\u6708\u00a0\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/29311493\">Serious Conditions in COVID-19 Accompanied With a Feature of Metabolic Syndrome.<\/a>Kei NakajimaJournal of clinical medicine research\u00a012(5) 273-275\u00a02020\u5e745\u6708\u00a0\u00a0<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-large-font-size\">2019<\/p>\n\n\n\n<ul id=\"block-a20a3584-d883-42b1-98c0-358b613724c1\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/5967544\">Impaired Glucose Metabolism in People with Extremely Elevated High-Density Lipoprotein Cholesterol and Low Alcohol Consumption: Results of the Kanagawa Investigation of Total Checkup Data from the National Database-3 (KITCHEN-3).<\/a>Nakajima K J Clin Med.\u00a08(11)\u00a02019\u5e7411\u67081\u65e5\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/23520874\">High Concentration of Serum Aspartate Aminotransferase in Older Underweight People: Results of the Kanagawa Investigation of the Total Check-Up Data from the National Database-2 (KITCHEN-2).<\/a>Shibata M, Nakajima K, Higuchi R, Iwane T, Sugiyama M, Nakamura TJournal of clinical medicine\u00a08(9)\u00a02019\u5e748\u670822\u65e5\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/23520877\">Adjustment for Waist Circumference Reveals a U-Shaped Association Between Glycated Hemoglobin Levels and Body Mass Index in Young Adults.<\/a>Higuchi R, Iwane T, Suwa K, Nakajima K. Canadian journal of diabetes\u00a043(3) 201-206\u00a02019\u5e744\u6708\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/23520875\">High Incidence of Diabetes in People with Extremely High High-Density Lipoprotein Cholesterol: Results of the Kanagawa Investigation of Total Checkup Data from the National Database-1 (KITCHEN-1).<\/a>Nakajima K, Higuchi R, Iwane T, Shibata M, Takada K, Sugiyama M, Matsuda M, Nakamura TJournal of clinical medicine\u00a08(3)\u00a02019\u5e743\u670819\u65e5\u00a0\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/23520876\">Kanagawa Investigation of the Total Check-up Data from the National database (KITCHEN): protocol for data-driven population-based repeated cross-sectional and 6-year cohort studies.<\/a>Nakajima K, Iwane T, Higuchi R, Shibata M, Takada K, Uda J, Anan M, Sugiyama M, Nakamura TBMJ open\u00a09(2) e023323\u00a02019\u5e742\u670821\u65e5\u00a0<\/li>\n\n\n\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/23520878\">Unhealthy eating habits around sleep and sleep duration: To eat or fast?<\/a>Nakajima KWorld journal of diabetes\u00a09(11) 190-194\u00a02018\u5e7411\u670815\u65e5\u00a0\u00a0\u00a0<span style=\"color: initial;\">\u00a0\u00a0<\/span><\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-cyan-blue-color has-text-color has-large-font-size\">2018<\/p>\n\n\n\n<ul id=\"block-a5fdcd8f-2984-4e15-9c57-70e45b90a11f\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/researchmap.jp\/read0136236\/published_papers\/23520879\">Potential common factors associated with predisposition to common cold in middle-aged and elderly Japanese: A community-based cross-sectional study.<\/a>Shibata M, Iwane T, Higuchi R, Suwa K, Nakajima KMedicine\u00a097(20) e10729\u00a02018\u5e745\u6708<\/li>\n<\/ul>\n\n\n\n<div style=\"height:44px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-left has-light-green-cyan-background-color has-background\" id=\"presentation\" style=\"font-size:20px;line-height:0\">\u5b66\u4f1a\u767a\u8868<\/p>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-link-color has-large-font-size wp-elements-b5079ef2b70e7ebc87044e3108f24d50\">2025<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308b4\u5e74\u5f8c\u306e\u4f4e\u4f53\u91cd\u306e\u5b9f\u614b\u3068\u5f71\u97ff\u3059\u308b\u56e0\u5b50\u306e\u30b3\u30db\u30fc\u30c8\u5185\u75c7\u4f8b\u7814\u7a76\uff0d\u95a2\u67711\u90fd6\u770c\u306eNDB \u30c7\u30fc\u30bf\u3088\u308a\uff0d\u00a0<br>\u7530\u4e2d\u88d5\u7f8e\u5b50, \u95a2\u6839\u611b\u8389, \u4e2d\u5cf6\u5553  \u65e5\u672c\u7dcf\u5408\u5065\u8a3a\u533b\u5b66\u4f1a\u7b2c54\u56de\u5927\u4f1a,\u00a02026\u5e741\u670823\u65e5<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4e2d\u9ad8\u5e74\u306b\u304a\u3051\u308b\u9244\u6b20\u4e4f\u6027\u8ca7\u8840\u304c\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\u306e\u767a\u75c7\u306b\u304a\u3088\u307c\u3059\u5f71\u97ff\uff1a\u95a2\u67711\u90fd6\u770c\u5927\u898f\u6a21\u30b3\u30db\u30fc\u30c8\u7814\u7a76<br>\u95a2\u6839\u611b\u8389, \u4e2d\u5cf6\u5553  \u7b2c79\u56de\u65e5\u672c\u6804\u990a\u30fb\u98df\u7ce7\u5b66\u4f1a\u5927\u4f1a, 2025\u5e745\u670825\u65e5<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u9006\u6d41\u6027\u98df\u9053\u708e\u30682\u578b\u7cd6\u5c3f\u75c5\u3001\u80a5\u6e80\u3001\u4f75\u5b58\u75be\u60a3\u3001\u304a\u3088\u3073\u6cbb\u7642\u85ac\u3068\u306e\u95a2\u4fc2\uff0d\u95a2\u67711\u90fd6\u770c\u306eNDB\u306e\u6d3b\u7528\uff0d<br>\u4e2d\u5cf6 \u5553, \u95a2\u6839\u611b\u8389  \u7b2c122\u56de\u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u8b1b\u6f14\u4f1a, 2025\u5e744\u670819\u65e5<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-large-font-size\">2024<\/p>\n\n\n\n<ul style=\"line-height:2\" id=\"block-15f9eef4-f764-4c12-b51d-26ea10197d5d\" class=\"wp-block-list\">\n<li>\u30d3\u30bf\u30df\u30f3\u6b20\u4e4f\u75c7\u304a\u3088\u3073\u4f4e\u30df\u30cd\u30e9\u30eb\u8840\u75c7\u3068\u5fc3\u623f\u7d30\u52d5\u306e\u95a2\u4fc2\uff1b\u95a2\u67711\u90fd6\u770cNDB\u3092\u7528\u3044\u305f\u7814\u7a76<br>\u95a2\u6839 \u611b\u8389\uff0c\u4e2d\u5cf6 \u5553\u3000\u7b2c78\u56de\u65e5\u672c\u6804\u990a\u30fb\u98df\u7ce7\u5b66\u4f1a\u5927\u4f1a\uff0c\u00a02024\u5e745\u670825\u65e5<\/li>\n\n\n\n<li>\u4e2d\u9ad8\u5e74\u3092\u5bfe\u8c61\u3068\u3057\u305f HbA1c \u304a\u3088\u3073\u4ed6\u306e\u30ea\u30b9\u30af\u56e0\u5b50\u306e\u6d88\u5316\u5668\u304c\u3093\u767a\u75c7\u306b\u53ca\u307c\u3059\u5f71\u97ff\uff1a\u95a2\u6771 1 \u90fd 6 \u770c\u306eNDB \u7814\u7a76<br>\u698e\u6238\u9ebb\u8863\uff0c\u95a2\u6839\u611b\u8389\uff0c\u4e2d\u5cf6\u5553\u3000\u7b2c67\u56de\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5e74\u6b21\u5b66\u8853\u96c6\u4f1a\uff0c\u00a02024\u5e745\u670818\u65e5<\/li>\n\n\n\n<li>\u70ad\u6c34\u5316\u7269\u8ca0\u8377\u306b\u3088\u308b\u553e\u6db2\u30a2\u30df\u30e9\u30fc\u30bc\u6d3b\u6027\u304a\u3088\u3073\u8840\u7cd6\u306e\u5909\u52d5<br>\u95a2\u6839\u611b\u8389\uff0c\u4e2d\u5cf6\u5553\u3000\u7b2c67\u56de\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5e74\u6b21\u5b66\u8853\u96c6\u4f1a\uff0c\u00a02024\u5e745\u670817\u65e5<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-green-cyan-color has-text-color has-large-font-size\">2023<a href=\"https:\/\/mcm-www.jwu.ac.jp\/~NDB-K7Ps\/blog\/\"><\/a><\/p>\n\n\n\n<ul style=\"line-height:2\" 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