PUBLICATIONS

研究成果

論文発表(主要論文を抜粋)

  • Aina Maria Mas, Enrique Goñi, Igor Ruiz de los Mozos, Aida Arcas, Luisa Statello, Jovanna González, Lorea Blázquez, Wei Ting Chelsea Lee, Dipika Gupta, Álvaro Sejas, Shoko Hoshina, Alexandros Armaos, Gian Gaetano Tartaglia, Shou Waga, Jernej Ule, Eli Rothenberg, María Gómez, and Maite Huarte.  ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins.  Nat. Commun. 14, 4447 (2023)  Link to DOI
  • Afaf Eladl, Yudai Yamaoki, Shoko Hoshina, Haruka Horinouchi, Keiko Kondo, Shou Waga, Takashi Nagata, and Masato Katahira.  Investigation of the interaction of human origin recognition complex subunit 1 with G-quadruplex DNAs of human c-myc promoter and telomere regions.  Int. J. Mol. Sci. 22, 3481 (2021).  Link to DOI
  • Shoko Hoshina, Kei Yura, Honami Teranishi, Noriko Kiyasu, Ayumi Tominaga, Haruka Kadoma, Ayaka Nakatsuka, Tomoko Kunichika, Chikashi Obuse, and Shou Waga.  Human origin recognition complex binds preferentially to G-quadruplex-preferable RNA and single-stranded DNA.  J. Biol. Chem. 288, 30161-30171 (2013). Link to DOI
  • Christpher Van, Shan Yan, W.Matthew Michael, Shou Waga, and Karlene A. Cimprich.  Continued primer synthesis at stalled replication forks contributes to checkpoint activation.  J. Cell Biol. 189, 233-246 (2010). Link to DOI
  • Akiko Zembutsu and Shou Waga.  De novo assembly of genuine replication forks on an immobilized plasmid in Xenopus egg extracts.  Nucleic Acids Res. 34, e91 (2006). Link to DOI
  • Noriko Sasakawa, Tomoyuki Fukui and Shou Waga.  Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest.  J. Biochem. 140, 95-103 (2006). Link to DOI
  • Shou Waga and Akiko Zembutsu.  Dynamics of DNA binding of replication initiation proteins de novo formation of pre-replicative complexes in Xenopus egg extracts.  J. Biol. Chem. 281, 10926-10934 (2006). Link to DOI
  • Tomoyuki Fukui, Kazumi Yamauchi, Taketo Muroya, Masahiro Akiyama, Hisaji Maki, Akio Sugino and Shou Waga.  Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts.  Genes to Cells 9, 179-191 (2004). Link to DOI
  • Asako Furukohri, Noriko Sato, Hisao Masai, Ken-ichi, Arai, Akio Sugino and Shou Waga.  Identification and characterization of Xenopus homolog of Dbf4, a regulatory subunit of Cdc7 protein kinase required for initiation of DNA replication.  J. Biochem. 134, 447-457 (2003). Link to DOI
  • Shou Waga, Taro Masuda, Haruhiko Takisawa, and Akio Sugino.  DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts.  Proc. Natl. Acad. Sci. USA 98, 4978-4983 (2001). Link to DOI
  • Shou Waga and Bruce Stillman.  The DNA replication fork in eukaryotic cells.  Annu. Rev. Biochem. 67, 721-51 (1998). Link to DOI
  • Tie-Hua Ni, William F. McDonald, Irene Zolotukhin, Thomas Melendy, Shou Waga, Bruce Stillman, and Nicholas Muzyczka.  Cellular protein required for adeno-associated virus DNA replication in the absence of adenovirus confection.  J. Virol. 72, 2777-2787 (1998). Link to DOI
  • Jens Oliver Funk, Shou Waga, Jo Beth Harry, Erik Espling, Bruce Stillman and Denise A. Galloway.  Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein.  Genes Dev. 11, 2090-2100 (1997). Link to DOI
  • Rong Li, Shou Waga, Gregory J. Hannon, David Beach and Bruce Stillman.  Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.  Nature, 371, 534-537 (1994).  Link to DOI
  • Shou Waga, Gregory J. Hannon, David Beach and Bruce Stillman.  The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA.  Nature, 369, 574-578 (1994). Link to DOI
  • Shou Waga and Bruce Stillman.  Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro.  Nature, 369, 207-212 (1994). Link to DOI
  • Shou Waga,Glenn Bauer and Bruce Stillman.  Reconstitution of complete SV40 DNA replication with purified replication factors.  J. Biol. Chem.269, 10923-10934 (1994). Link to DOI

学会発表(最近数年間の発表のみ抜粋)

  • 和賀祥、堀之内遥香、田野中茜、松本和果奈.ヒトORCの天然変性領域の機能に関する生化学的な解析.第43回日本分子生物学会年会(2020年12月2-4日、オンライン開催)
  • Afaf Eladl, Yudai Yamaoki, Shoko Hoshina, Haruka Horinouchi, Keiko Kondo, Omar Eladl, Takashi Nagata, Shou Waga, Masato Katahira.  Investigation of the interaction between human origin recognition complex subunit 1 and G-rich DNAs.  第43回日本分子生物学会年会(2020年12月2-4日、オンライン開催)
  • 和賀祥.複製開始タンパク質ORCによるグアニン四重鎖への結合.第93回日本生化学会大会(2020年9月14-16日、オンライン開催)
  • 堀之内遥香、山室優香、飯野美穂、川上広宣、片山勉、由良敬、和賀祥.ヒトORC1とORC2におけるグアニン四重鎖形成可能な1本鎖DNAとの結合に関与するドメインの解析.第42回日本分子生物学会年会(2019年12月3-6日、福岡国際会議場)
  • 堀之内遥香、女部田寛子、飯野美穂、由良敬、和賀祥.ヒトORCのグアニン四重鎖形成1本鎖DNA形成活性の生化学的な解析.第41回日本分子生物学会年会(2018年11月28-30日、横浜パシフィコ)
  • 武江ことみ、中塚萌、坂本麻美、堀之内遥香、和賀祥.ヒトORCのDNA超らせん誘導活性の生化学的な解析.第41回日本分子生物学会年会(2018年11月28-30日、横浜パシフィコ)